PhD in Neurosciences
Program Requirements

The requirements for a PhD in Neurosciences are exciting and challenging.

First Year

During the first year, PhD students are expected to complete the first year core curriculum of the graduate school. Students also explore research opportunities in the department through elective laboratory rotations. After the first year, students will select the area in which research and preparation of the dissertation will be accomplished. To aid in this, the student will attend a weekly seminar (seminar/journal), where concepts and introductory methodology involved in neuroscience are presented. In addition, all students are encouraged to undertake special projects with members of the faculty before selecting an advisor.

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Second Year

During the second year, students will take PHYSO-731 and PHYSO-741. Students may elect to take other courses in neuroscience and cell and molecular biology, to provide additional breadth of knowledge, as well as specialized in-depth learning experience in areas pertinent to the research problem.

Once each year, all students are required to present a seminar dealing with the dissertation research or other topic. The qualifying examination for admission to degree candidacy will normally be administered beginning in the Summer session of the second year of the program. This examination will be in two parts: written and oral.

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Course Overviews

In addition to participation in the common curriculum course that all first year PhD students are required to take, the department offers several advanced courses:

View course overviews

In addition to these graduate level courses, there are additional course offerings in Neurosciences that the department teaches within the Colleges of Medicine and Dentistry.

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Qualifying Examinations

The qualifying examination will consist of both a written and an oral component. While each component will be administered separately, the examination is designed to be an integrated process.

Written Examination

Prerequisite Prior to this examination, the student must satisfactorily complete the first year graduate school curriculum and the core Neuroscience program curriculum and be in good academic standing (3.0 overall GPA or better, and a GPA of at least 3.0 for the program courses that have been taken). This examination will ordinarily be taken sometime between the end of the fourth semester and the beginning of the sixth semester of the program.
Objective
  • To assess the student's general knowledge base in the Neurosciences
  • To examine the ability of the student to integrate information in that knowledge base
Committee members Each year, a qualifying examination committee will be appointed by the department chair. The committee will consist of 4 faculty members from the Department of Neurosciences. The committee will put together the written qualifying examination for that year's students.
Examination Format

The qualifying examination committee will solicit examination questions from the departmental faculty involved in graduate education. The submitted questions will be reviewed and selected by the committee. All students will take the same examination at the same time. The examination will ordinarily be taken in the month of May at the end of the fourth semester of the program (not including summer). The examination will be administered over a 3-day period. Each day, students will be given 3 questions, from which they must answer 2. One of these questions will be a required question that all students must answer. Each day's testing will consist of a 4-hour morning and afternoon session with a 1-hour break for lunch. Typically, the required question would be given during the morning session and the optional questions given during the afternoon session. The faculty member who wrote the particular question will grade the student's answer.

Committee Feedback

At the completion of the examination, the examination committee will meet to evaluate the performance of the student. The committee will make a recommendation to the departmental faculty as to whether the student may proceed to the oral examination. The departmental graduate faculty will then vote on whether the student has passed the written examination.

Once the student has passed the written examination, a summary of the strengths and weaknesses of the student's performance will be compiled and forwarded to the appropriate oral examination committee along with the student's graded examination questions.

A critique of the student's performance on each examination question will be provided to the student. However, an individual grade for each question will not be provided; only an overall pass/fail for the entire examination.

Failure of Examination If a student fails the written qualifying examinations, the student must petition the departmental examination committee to be allowed to retake the examination. The student's progress in the program will be a major factor in determining whether a student will be permitted to retake the examination. Other factors will include the recommendation form the student's advisor, an evaluation of the student's grades, the student's participation in seminars and research committee meetings, and evidence for research progress. The format of the written re-examination will be determined by the examination committee. The decision to deny a student the opportunity to retake the written examinations must be unanimous. If the examination is failed after the second attempt, the student will be dismissed from the Neurosciences doctoral program.
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Oral Examination

After successfully completing the written examination, the student will take an oral examination with their advisory committee. This examination will typically last 2-3 hours. The oral examination must be completed by the beginning of the fall semester.
Committee Each student will have an individual oral examination committee. Typically, this committee will also serve as the student's dissertation committee, but the student may elect to make changes in the makeup of the dissertation committee after successfully completing the oral examinations. The oral examination committee will consist of a minimum of 4 faculty members, of whom at least 3 must be members of the graduate faculty and in the Department of Neurosciences.
Purpose
  • To test the ability of the student to think on his/her feet
  • To explore weaknesses in their knowledge base that were identified in the written examination

The committee will also have the prerogative to request one or more non-committee faculty to attend the oral. Following the oral examination, the committee will vote on whether the student passed the oral examination.

It is important to view the written and orals as an integrated examination. In addition, this oral examination is separate from the oral defense of the student's dissertation proposal, and should cover a broad array of topics.

Failure of Examination If the student fails his/her oral examination, the same appeal process as described for failure of the written examination will be followed with the exception that the petition will be directed to his/her oral examination committee.
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Defense of Dissertation Proposal

Prerequisite Prior to the defense, the student must have successfully passed the written qualifying examanation. The defense of the dissertation proposal will ordinarily be taken no longer than 6 months after the written qualifying examination.
Committee Members The dissertation committee will consist of a minimum of 4 faculty members, of whom at least 3 must be members of the Department of Neurosciences. The student's major advisor normally chairs this committtee.
Written Proposal

The student's committee will have a major responsibility to ensure that the student is as ready as possible to submit a well-thought-out proposal and to defend that proposal and demonstrate a knowledge of neuroscience and experimental design. The proposal will be written in National Institutes of Health grant format (Individual National Research Service Award Application; Form PSH 416-1). The Web address for the appropriate forms is http://grants.nih.gov/grants/funding/416/phs416.htm

  1. Specific Aims. State the specific purposes of the research proposal and the hypotheses to be tested.
  2. Background and Significance. Sketch briefly the background to the proposal. State concisely the importance of the research described in this application by relating the specific aims to broad, long-term objectives. This section should be 4-7 pages (a little longer than recommended for actual grants to allow more space for demonstrating a knowledge of the relevant literature). The literature survey should include relevant information, but need not be exhaustive. Literature citations should be by author and year in this section (two authors or et al., as necessary). Do not number citations.
  3. Preliminary studies (1-4 pages). This will vary a great deal because some students will be further along by the time they complete this section.
  4. Research Design and Methods. Provide an outline of:
    • Research design and the procedures to be used to accomplish the specific aims.
    • Tentative sequence for the investigation.
    • Statistical procedures by which the data will be analyzed.
    • Any procedures, situations, or materials that may be hazardous to personnel and the precautions to be exercised; and Any courses planned which support the research training experience.
    • Potential experimental difficulties should be discussed together with alternative approaches that could achieve the desired aims.
  5. Literature Cited: Maximum 6 pages. Citations should be listed alphabetically by first author and include titles.
Oral Presentation
  1. A 30-40 minute seminar presentation of the proposal by the student followed immediately by an oral discussion.
  2. The discussion (2 hours maximum duration) will begin with questions from all those in attendance and then proceed to questions from committee members. All of the doctoral committee members must be present. Questions may broadly cover aspects of neuroscience and research design, but primarily will be oriented towards the proposal. After this phase of the examination, the dissertation committee will adjourn to discuss the candidate's performance and to vote.

The candidate may be questioned further during this second phase of the examination. In the event a student fails the proposal defense, the committee will either recommend the student be given an opportunity to reschedule the defense, or the student will be dropped as a Ph.D. candidate in the Neurosciences Program (a terminal M.S. would be possible). At least three months must elapse between a failed defense and the re-scheduled defense. The proposal defense may be taken a maximum of two times. Two failures result in termination of enrolment in the Graduate School.

Careful scheduling of the proposal defense is very important to enable board participation by the members of the department. Dissertation proposals must be distributed to the doctoral committee and be available to the entire program faculty at least two weeks before the examination.

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Final Defense of Dissertation

After the dissertation committee has accepted the dissertation proposal, the student will keep the committee informed about the progress of the dissertation research through semi-annual meetings, culminating in the dissertation defense. The student's committee will have a major responsibility in ensuring that the student is ready to submit a well-written dissertation in the area of experimental neuroscience and to defend that dissertation orally.

Final dissertation copies must be distributed to the doctoral committee and be available upon request to the entire program faculty at least two weeks before the defense. After the committee members have read the dissertation, they will provide the student with oral and/or written feedback that may require revisions to the document. When the dissertation is submitted, the date and location of the defense should be carefully scheduled in order to enable broad participation by the faculty. The defense is public and the time and place will be announced to the MUSC community via a memorandum.

All of the doctoral committee members must be present at the defense in accordance with the Graduate School rules. The defense consists of a seminar-style presentation of the dissertation research by the candidate (30-45 minutes) followed by questions. All those in attendance are invited to question the candidate. In addition to questions about the dissertation research, questions in relevant fields of neuroscience may be entertained. After this phase of the defense, all those who are not members of the graduate faculty are excused and the candidate is questioned further. The candidate is then excused and the dissertation committee proceeds to discuss and vote on the candidate's performance.

Thesis Requirement in the Masters program for Neuroscience:

Masters Candidates will submit an original manuscript of their work to a peer reviewed scientific journal as a requirement for completion of the program of study. This manuscript should be written by the student as first author and with guidance from the major advisor. The manuscript will be submitted to the advisory committee for their critique and approval.

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Master of Science

While the graduate program is primarily oriented toward obtaining a PhD degree, a program of study leading to a Master's Degree is offered on a more limited basis. This program can be completed within two years, and consist of successful completion of selected coursework and an original research program. While the graduate school does not provide stipend support for MS students, support is sometimes available from research grants awarded to departmental faculty.

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